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Lambert-Eaton Myasthenic syndrome in a child with an autoimmune phenotype

✍ Scribed by Hoffman, William H. ;Helman, Sandra W. ;Sekul, Elizabeth ;Carroll, James E. ;Vega, Roger A.

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
62 KB
Volume
119A
Category
Article
ISSN
0148-7299

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Lambert-Eaton myasthenic syndrome (LEMS) is a neurological disorder characterized by reduced presynaptic release of acetylcholine.' Antibodies measured with o-conotoxin GVIA (GVIA), a long-lasting N-type calcium channel blocker, have been detected in 44-90% of patients with LEMS and in 10-42% of pat