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Lactogens protect rodent and human beta cells against glucolipotoxicity-induced cell death through Janus kinase‐2 (JAK2)/signal transducer and activator of transcription-5 (STAT5) signalling

✍ Scribed by N. Guthalu Kondegowda; A. Mozar; C. Chin; A. Otero; A. Garcia-Ocaña; R. C. Vasavada


Book ID
113017795
Publisher
Springer
Year
2012
Tongue
English
Weight
457 KB
Volume
55
Category
Article
ISSN
0012-186X

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Although the cytokine-inducible transcription factor signal transducer and activator of transcription 5 (STAT5) promotes proliferation of a wide range of cell types, there are cell-specific and context-specific cases in which loss of STAT5 results in enhanced cell proliferation. Here, we report that