Lactate dehydrogenase in preimplantation rabbit embryos

✍ Scribed by Gilbert A. Schultz; Leon W. Browder

• Publisher: Springer
• Year: 1975
• Tongue: English
• Weight: 474 KB
• Volume: 13
• Category: Article
• ISSN: 0006-2928
• DOI: 10.1007/bf00484924

✦ Synopsis

Unfertilized eggs and early embryos up to the 2-day (16-cell) cleavage stage of development in the rabbit contain predominantly the most eathodal lactate dehydrogenase isoenzyme made up of A-type subunits. Following early cleavage there is a progressive increase in total LDH activity in the embryo as development proceeds through 4-and 6-day blastoeyst stages. This is accompanied by an increase in the amounts of B-type subunits and a concomitant shift in the lactate dehydrogenase isoenzyme electrophoretic pattern toward the anodal isoenzyme types.