Lack of tolerance to a soluble MHC class I antigen
β Scribed by Donald W. Mann; James Forman
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 288 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0167-5699
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## Epstein -Barr virus (EBV) is present in Reed-Sternberg (RS) cells of a substantial proportion of Hodgkin's lymphoma cases. Most EBV-positive cases are also MHC class I-positive, whereas the majority of EBV-negative cases lack detectable levels of MHC class I expression. Application of the SAGE t
We investigated the biochemistry of naturally occurring major histocompatibility complex (MHC) class I molecules in human serum and established a quantitative enzyme-linked immunoassay (ELISA) to determine soluble human leukocyte antigen (HLA) concentration. Peptides of 46,40, 37, 35, and 12 kDa we