✦ LIBER ✦

Lack of thrombohemorrhagic phenomena complicating childhood solid tumors

✍ Scribed by Dr. Diane M. Komp

Publisher: John Wiley and Sons
Year: 1974
Tongue: English
Weight: 330 KB
Volume: 33
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(197404)33:4<1086::aid-cncr2820330429>3.0.co;2-v

No coin nor oath required. For personal study only.

✦ Synopsis

Forty children with disseminated solid tumors (neuroblastoma, Wilms' tumor, rhabdomyosarcoma, lymphoma, Ewing's sarcoma, histiocytosis-X, osteogenic sarcoma, and retinoblastoma) were studied for evidence of disseminated intravascular coagulation (DIG). Fibrinogen, factor V, factor VIII, cryofibrinogen, and fibrin/fibrinogen degradation product levels did not support the diagnosis of DIC in any patient. Abnormalities of platelets, serial thrombin time, and factors I1 and VII-X were related to disease process or therapy. DTC does not appear to be common in children with metastatic solid tumors.

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