## Purpose: Combination chemotherapy with vincristine, etoposide, and high-dose, escalating cyclophosphamide (vetopec) is an effective regimen in pediatric patients with high-risk solid tumors. the toxicity of the regimen is predominantly haematologic. this study addressed the role of recombinant h
A dose-intensive, cyclophosphamide-based regimen for the treatment of recurrent/Progressive or advanced solid tumors of childhood : A report from the Australia and New Zealand Children's Cancer Study Group
โ Scribed by Paul A. Carpenter; Les White; Geoffrey B. McCowage; Vimala Nayanar; Ian Toogood; Peter J. Shaw; Lianne Lockwood; Karen Tiedemann; for the Australia; New Zealand Children's Cancer Study Group
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 130 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
โฆ Synopsis
promising salvage regimen. Continued accrual of patients and increased duration of follow-up has resulted in substantial experience with VETOPEC.
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## Background: This phase i trial was developed to determine the safety, biologic activity, and effects on hematopoietic recovery of pixy321 following ifosfamide, carboplatin, and etoposide chemotherapy for children with recurrent or refractory solid tumors. ## Methods: Children (age < 22 years a