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Lack of T Cell Tolerance in Mice Exposed to a Protein Antigen through Lactation

✍ Scribed by Marion Ryelandt; Dominique De Wit; Marcelle Van Mechelen; Georgette Vansanten; Jacques Urbain; Oberdan Leo


Book ID
112239229
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
428 KB
Volume
162
Category
Article
ISSN
0008-8749

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## Abstract ## Background Host immune responses to foreign gene products have been shown to lead to the elimination of genetically modified cells, and are a major barrier to successful therapeutic gene therapy. We have shown that immunological tolerance to retrovirally transduced cell surface prot