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T cell suppression as a mechanism for tolerance to MUC1 antigen in MUC1 transgenic mice

โœ Scribed by Dongshu Chen; Shigeo Koido; Yongqing Li; Sandra Gendler; Jianlin Gong


Book ID
110234331
Publisher
Springer US
Year
2000
Tongue
English
Weight
145 KB
Volume
60
Category
Article
ISSN
0167-6806

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Background EBV immortalized B-cells can be used as antigen presenting cells (APC) to stimulate speciยฎc T-cell responses. Mini-Epstein-Barr virus (mini-EBV) plasmids contain all functional elements of Epstein-Barr virus (EBV) necessary to immortalize B-cells in vitro. These immortalized B-cells are i