Colony formation and growth in vitro by C57B1 mouse bone marrow cells were analysed following stimulation by a standard dose of sexum colony stimulating factor. Under restricted conditions, colony crowding was observed to potentiate colony growth rates. The addition of thymic or lymph node lymphoid
Lack of response of bone marrow, in vitro, to growth factors in congenital neutropenia
β Scribed by James Chang; L. H. Coutinho; Michael Dexter; Dr Alan W. Craft; Michael M. Reid
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 143 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0361-8609
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## Abstract Single cells from developing two day granulocytic bone marrow colonies were transfered in agar cultures. After three to five days, 48 of 239 transfered single cells had transformed to single macrophages or proliferated to form aggregates of pure macrophages or mixed macrophageβgranulocy