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Lack of MDM2 amplification in human leukaemia

✍ Scribed by Susan A. Ridge; Martin Dyer; Mel F. Greaves; Leanne M. Wiedemann


Book ID
114713563
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
258 KB
Volume
86
Category
Article
ISSN
0007-1048

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## Abstract Amplification of the 12q13–15 region is a common event in several human tumors including liposarcomas, gliomas, and osteosarcomas. We have demonstrated high‐level amplification of 12q14 in a subset of uncultured malignant melanomas (3 of 53). High‐resolution mapping of the amplicon usin