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Lack of linkage between idiopathic generalized epilepsies and the gene encoding the neural cell adhesion molecule

✍ Scribed by Thomas Sander; Thomas Hildmann; Dieter Janz; Amedeo Bianchi; Gerhard Bauer; Alejandro Scaramelli; Gertrud Beck-Mannagetta


Book ID
103932493
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
534 KB
Volume
25
Category
Article
ISSN
0920-1211

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πŸ“œ SIMILAR VOLUMES


Exclusion of linkage between idiopathic
✍ Thomas Sander; Thomas Hildmann; Dieter Janz; Thomas F. Wienker; Amedeo Bianchi; πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 685 KB

Hereditary factors play a major role in the etiology of idiopathic generalized epilepsies (IGEs). The pivotal function of ionotropic gamma-aminobutyric acid type A receptors (GABRs) in inhibitory neurotransmission in the mammalian central nervous system suggests that they may be involved in epilepto

Association analysis of exonic variants
✍ Sander, T.; Peters, C.; KοΏ½mmer, G.; Samochowiec, J.; Zirra, M.; Mischke, D.; Zie πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 26 KB πŸ‘ 2 views

The gene encoding the GABA B receptor (GABA B R1) maps close to the HLA-F locus on chromosome 6p21.3 in the same region to which a major susceptibility locus for common subtypes of idiopathic generalized epilepsy (IGE), designated as EJM1, has been localized. Moreover, animal models suggest that the