Lack of interaction between buspirone and triazolam
β Scribed by Boulenger, J.P.; Gram, L.; Jolicoeur, F.B.; Zarifian, E.
- Book ID
- 123553138
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 81 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0924-977X
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## Abstract The present study was designed to evaluate possible pharmacokinetic and pharmacodynamic interactions between buspirone administered repeatedly and triazolam given acutely. Ten healthy male volunteers participated in the study and received 0.25 mg of triazolam orally after a oneβweek pre
Four normal volunteers each received three intraduodenal infusions of 0.5 mg triazolam solutions. Three treatments were: 1. a pH 2.3 solution in which 47 per cent of the dose had hydrolysed to form a triazolo-benzophenone (TB); 2. a pH 6.0 solution containing negligible TB; 3. the p H 6.0 solution