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Lack of Homozygously Inactivated p73 in Single-Copy MYCN Primary Neuroblastomas and Neuroblastoma Cell Lines

✍ Scribed by Kong, Xiao-Tang; Valentine, Virginia A.; Rowe, Susan T.; Valentine, Marcus B.; Ragsdale, Susan T.; Jones, Bart G.; Wilkinson, Deborah A.; Brodeur, Garrett M.; Cohn, Susan L.; Look, A. Thomas


Book ID
122362955
Publisher
Neoplasia Press
Year
1999
Tongue
English
Weight
417 KB
Volume
1
Category
Article
ISSN
1522-8002

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Homozygous deletion and expression of PT
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## Abstract Neuroblastoma is the most common pediatric solid tumor. Although many allelic imbalances have been described, a bona fide tumor suppressor gene for this disease has not been found yet. In our study, we analyzed 2 genes, PTEN and DMBT1, mapping 10q23.31 and 10q25.3‐26.1, respectively, wh