✦ LIBER ✦

Lack of ETV6 (TEL) gene rearrangements or p16INK4A/p15INK4B homozygous gene deletions in infant acute lymphoblastic leukemia

✍ Scribed by Hunger, S P; Maloney, K W; Rubnitz, J E; Cleary, M L; Frankel, L S; Hakami, N; Link, M P; Pullen, D J

Book ID: 110053537
Publisher: Nature Publishing Group
Year: 1997
Tongue: English
Weight: 487 KB
Volume: 11
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2400687

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Different patterns of homozygous p16INK4

Different patterns of homozygous p16INK4A and p15INK4B deletions in childhood acute lymphoblastic leukemias containing distinct E2A translocations

✍ Maloney, K W; McGavran, L; Odom, L F; Hunger, S P 📂 Article 📅 1998 🏛 Nature Publishing Group 🌐 English ⚖ 123 KB

Homozygous deletion of the p16INK4a and

Homozygous deletion of the p16INK4a and the p15INK4b tumour suppressor genes in a subset of human sporadic cutaneous malignant melanoma

✍ Wagner; Wagner; Briedigkeit; Goos 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 453 KB

Chromosome 9p21 is frequently deleted in malignant melanoma, and one familial malignant melanoma gene has been linked to 9p21-22. Recently, the cyclin D-dependent kinase inhibitors (CDKIs) p16INK4a and p15INK4b have been localized within chromosome 9p21, and the presence of p16INK4a point mutations

ABL oncogene amplification with p16INK4a

ABL oncogene amplification with p16INK4a gene deletion in precursor T-cell acute lymphoblastic leukemia/lymphoma: Report of the first case

✍ Hee-Jin Kim; Hee-Yeon Woo; Hong-Hoe Koo; Eun-Young Tak; Sun-Hee Kim 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 95 KB 👁 2 views

## Abstract Gene amplification is a relatively rare event in hematologic malignancies. The __ABL__ gene on chromosome band 9q34 is a proto‐oncogene and is the well‐known translocation partner of the __BCR__ gene on 22q11 giving rise to t(9;22)(q34;q11), which is the hallmark of chronic myeloid leuk

Methylation of the multi tumor suppresso

Methylation of the multi tumor suppressor gene-2 (MTS2, CDKN1, p15INK4B) in childhood acute lymphoblastic leukemia

✍ Iravani, M; Dhat, R; Price, C M 📂 Article 📅 1997 🏛 Nature Publishing Group 🌐 English ⚖ 367 KB

Deletion of the Ink4-locus (the p16ink4a

Deletion of the Ink4-locus (the p16ink4a, p14ARF and p15ink4b genes) predicts relapse in children with ALL treated according to the Nordic protocols NOPHO-86 and NOPHO-92

✍ Calero Moreno, T M; Gustafsson, G; Garwicz, S; Grandér, D; Jonmundsson, G K; Fro 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 192 KB

Establishment of a novel human B-cell li

Establishment of a novel human B-cell line (OZ) with t(14;18)(q32;q21) and aberrant p53 expression was associated with the homozygous deletions of p15INK4B and p16INK4A genes

✍ M. Nagai; M. Fujita; M. Ohmori; S. Matsubara; M. Taniwaki; S. Horiike; T. Tasaka 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 174 KB 👁 1 views

The novel human pre-B cell line OZ was established from a patient with an aggressive form of non-Hodgkin's lymphoma. Karyotypic analysis of both the primary tumour and OZ cells revealed several marker chromosomes, including the t(14;18)(q32;q21) translocation, which involves the Bcl-2 gene, and alte