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Lack of EGFR gene mutations in exons 19 and 21 in esophageal (Barrett's) adenocarcinomas

✍ Scribed by F. A. Pühringer-Oppermann; H. J. Stein; M. Sarbia

Book ID: 108980907
Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 71 KB
Volume: 20
Category: Article
ISSN: 1120-8694
DOI: 10.1111/j.1442-2050.2007.00630.x

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## Abstract Hypermethylation of secreted frizzled‐related proteins (__SFRP__) genes frequently occurs with several cancers but has not been studied in esophageal adenocarcinoma or its precursor—Barrett's esophagus. To explore the role of __SFRP__ methylation in the neoplastic progression of Barrett