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Lack of effect of tricyclic antidepressants on serum prolactin levels

✍ Scribed by Herbert Y. Meltzer; Songkait Piyakalmala; Paul Schyve; Victor S. Fang

Publisher: Springer
Year: 1977
Tongue: English
Weight: 283 KB
Volume: 51
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00431738

No coin nor oath required. For personal study only.

✦ Synopsis

A previous report indicated that the tricyclic antidepressants imipramine and amitriptyline markedly increased plasma prolactin levels in man. We found no increases after acute or chronic treatment with either drug in usual clinical doses. The results indicate that blockade of serotonin reuptake does not affect basal prolactin levels in man.

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