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Lack of effect of long-term glutathione administration on aflatoxin B1-induced hepatoma in male rats

✍ Scribed by Gunter Wagner; Hartmut Frenzel; Heribert Wefers; Helmut Sies

Book ID: 114009266
Publisher: Elsevier Science
Year: 1985
Tongue: English
Weight: 700 KB
Volume: 53
Category: Article
ISSN: 0009-2797
DOI: 10.1016/s0009-2797(85)80084-3

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Glutathione S-transferase (GST) plays a major role in the detoxification of the potent hepatocarcinogen aflatoxin B(1) (AFB(1)). This study evaluated the effects of intermittent exposures to AFB(1) on hepatic and testicular GST in rats. Male Fischer 344 rats were fed diets containing AFB(1) (0, 0.01