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Lack of effect of diphenylhydantoin ingestion on vesical transitional epithelium in the rat

✍ Scribed by D. F. McDonald

Publisher
John Wiley and Sons
Year
1969
Tongue
English
Weight
168 KB
Volume
1
Category
Article
ISSN
0022-4790

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✦ Synopsis

Seizure-prone patients may be chronically treated with diphenylhydantoin, a mitogenic agent excreted in the urine. Chronic ingestion of diphenylhydantoin by 64 rats failed to demonstrate vesical epithelial tumor formation under conditions which demonstrate the tumorigenicity of other vesical carcinogens. Vesical neoplasms

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