Pharmacokinetics and hepatic first-pass
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Inmaculada Soria; Dr. Cheryl L. Zimmerman
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Article
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1995
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John Wiley and Sons
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English
โ 300 KB
๐ 2 views
Studies were designed to allow an in vivo estimation of the hepatic extraction ratio and to test the hypothesis that the pharmacokinetic parameters of (-)-CBV are significantly different during anesthesia. (-)-CBV was administered as an IV bolus followed by IV infusion into either the portal (n = 3)