𝔖 Bobbio Scriptorium
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Lack of effect of paracetamol on the pharmacokinetics of chloramphenicol.

✍ Scribed by CM Stein; DP Thornhill; P. Neill; NZ Nyazema

Book ID
117944826
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
402 KB
Volume
27
Category
Article
ISSN
0306-5251

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Plasma and urine concentrations of codeine and its measurable metabolites were determined by HPLC in six healthy subjects after a single 30 mg oral dose of codeine either alone or after 7 doses of 1 g paracetamol 8 hourly. After codeine alone, the t1/2 (h), AUC (mumol.l-1.h) and CLR (ml.min-1) for c