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Lack of correlation between cytotoxic T-lymphocyte precursor frequency and acute graft versus host disease post bone marrow transplant


Book ID
123078432
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
84 KB
Volume
37
Category
Article
ISSN
0198-8859

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Selective depletion of marrow-T cytotoxi
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In vitro depletion of mature pan-T lymphocytes has been widely and successfully used to prevent acute graft-versus-host disease (GVHD) after allogeneic bone-marrow transplantation (BMT). However, this procedure has been associated with a high incidence of graft failure and leukemic relapse. In this