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Lack of association of the UCHL-1 gene with Parkinson's disease in a greek cohort: A haplotype-tagging approach

✍ Scribed by Georgia Xiromerisiou; Elli Kyratzi; Efthimios Dardiotis; Maria Bozi; Vana Tsimourtou; Eleftherios Stamboulis; Styliani Ralli; Demetrios Vassilatis; Vanessa Gourbali; Persa-Maria Kountra; Kostas Fountas; Alexandros Papadimitriou; Leonidas Stefanis; Georgios M. Hadjigeorgiou


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
573 KB
Volume
26
Category
Article
ISSN
0885-3185

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✦ Synopsis


The disorders of voice and speech in Parkinson's disease (PD) result from involvements in several subsystems including respiration, phonation, articulation, and prosody. [1][2][3] We investigated the feasibility of acoustic measures for the identification of voice and speech disorders in PD, using a quick vocal test consisting of sustained phonation, diadochokinetic task, and running speech. Various traditional and novel acoustic measurements have been designed in order to be gender independent, represent all speech subsystems, reduce the time required for voice investigation, and provide a reliable automated assessment in practice. 4


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