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Lack of association between the −759C/T polymorphism of the 5-HT2C receptor gene and olanzapine-induced weight gain among Korean schizophrenic patients

✍ Scribed by Y.-M. Park; J.-H. Cho; S.-G. Kang; J.-E. Choi; S.-H. Lee; L. Kim; H.-J. Lee


Book ID
108849090
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
74 KB
Volume
33
Category
Article
ISSN
0269-4727

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Transgenic mice lacking a functional 5-HT 2c receptor gene are extremely susceptible to audiogenic seizures, suggesting that 5-HT 2c receptors mediate inhibition of neuronal network excitability. The present association study tested the hypothesis that a Cys23Ser substitution polymorphism within the