BACKGROUND: Genetic variation in the folate metabolic pathway may influence the risk of congenital heart defects. This study was undertaken to assess the associations between the inherited and maternal genotypes for variants in folate-related genes and the risk of a composite heart phenotype that in
Lack of Association Between Folate Receptor Autoantibodies and Conotruncal Congenital Heart Defects
β Scribed by Laura B. Lewandowski, Darshak Sanghavi
- Book ID
- 120763886
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 199 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0172-0643
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Defects of neural tube closure are among the most common of all human malformations. Epidemiological and genetic studies indicate that most of these defects are multifactorial in origin with genetic and environmental causes. Although periconceptional supplementation of the maternal diet with folic a