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Lack of evidence of association between MTHFR C677T polymorphism and congenital heart disease in a TDT study design

✍ Scribed by Alexandre C. Pereira; José Xavier-Neto; Sônia M. Mesquita; Glória F.A. Mota; Antônio Augusto Lopes; José Eduardo Krieger


Book ID
116543646
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
85 KB
Volume
105
Category
Article
ISSN
0167-5273

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## Abstract Different lines of evidence indicate that methylenetetrahydrofolate reductase (__MTHFR__) functional gene polymorphisms, causative in aberrant folate–homocysteine metabolism, are associated with increased vulnerability to several heritable developmental disorders. Opposing views are exp