Lack of association between bleomycin hydrolase gene polymorphism and Alzheimer's disease in Japanese people
β Scribed by Yoshio Namba; Yasuyoshi Ouchi; Takashi Asada; Hiroaki Hattori; Akira Ueki; Kazuhiko Ikeda
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 139 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Granulin protein plays an important role in neurite outgrowth and neuronal survival. Recently, it was shown that mutations in __granulin__ (__GRN__) gene cause tauβnegative frontotemporal dementia supporting the idea that granulin is involved in neurodegeneration. Here we have investiga
## 817 ated with increased risk for AD, at least in the Korean population. Nevertheless, it cannot be excluded that the association between IL-1A (-889) C/T polymorphism and AD observed in previous studies might be the result of linkage disequilibrium with a yet unidentified gene on chromosome 2.