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Labelling of thioxanthine, thioguanine and 2-thio-uracil with 35S by isotopic exchange

✍ Scribed by C. Choitan; I. Zamfir

Publisher
John Wiley and Sons
Year
1968
Tongue
French
Weight
213 KB
Volume
4
Category
Article
ISSN
0022-2135

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✦ Synopsis

The labelling of TX and TG with 35S has been performed by Moravek and Nejedly ( l ) , by isotopic exchange with elemental radiosulphur in boiling pyridine solution. The authors do not give any indications regarding the kinetics and the exchange yields. 2-Thio-uracil has been labelled only by synthesis in 1958 by Ziegler ( 2 ~.

We have done this study, aiming to find some simpler labelling methods than those described in the literature.

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