Labelling of proteins with 11C in high specific radioactivity: [11C]albumin and [11C]transferrin
✍ Scribed by Göran Westerberg; Bengt Långström
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 895 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0969-8043
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The paper describes the first method for n.c.a. "C-ring labelling of benzenoid compounds having a reactive group for further derivatization by use of the known principle of synchronous six-electron cyclization of hexatriene systems into aromatics. Nitro-["Clmethane (1) prepared from cyclotron-produc
Starting with "CO , [carboxyl-llC1-nicotinic acid amide was synthesized via 3-p$ridyl-lithium in practically carrierfree amounts within 60 minutes. Overall radiochemical yields between 20% and 30% were obtained. Identification and purification of the labelled product was carried out by high pressure