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Labelling, in vivo imaging and metabolism of spiegelmers

✍ Scribed by B. Tavitian; B. Kühnast; S. Klussmann; F. Dollé; I. Doignon; B. Wlotzka; B. Rousseau

Book ID
112132711
Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
130 KB
Volume
44
Category
Article
ISSN
0022-2135

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## Abstract Spiegelmers are high‐affinity l‐enantiomeric oligonucleotide ligands (aptamers) that display high resistance to enzymatic degradation compared to d‐oligonucleotides. Spiegelmers belong to the third generation of aptamers, and are currently extensively investigated as potential therapeut