𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vivo biodistribution and pharmacokinetics of18F-labelled Spiegelmers: a new class of oligonucleotidic radiopharmaceuticals

✍ Scribed by Raphaël Boisgard; Bertrand Kuhnast; Stefan Vonhoff; Chéraz Younes; Françoise Hinnen; Jean-Marc Verbavatz; Bernard Rousseau; Jens Peter Fürste; Britta Wlotzka; Frédéric Dollé; Sven Klussmann; Bertrand Tavitian


Publisher
Springer
Year
2004
Tongue
English
Weight
351 KB
Volume
32
Category
Article
ISSN
0340-6997

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis and biodistribution of 18F-lab
✍ Paul A. Jerabek; Timothy B. Patrick; Michael R. Kilbourn; Douglas D. Dischino; M 📂 Article 📅 1986 🏛 Elsevier Science ⚖ 775 KB

Three 18F labeled fluoronitroimidazoles have been prepared as potential in vivo markers of hypoxic cells in tumors, and ischemic areas of the heart and brain. 1-(2-Nitroimidazolyl)-3-[18F]fluoro-2-hydroxypropanol (18F]fluoro-normethoxymisonidazole) 4, 1-(2-[18F]fluoroethyl)-2-nitroimidazole 7, and 1

Radiosynthesis and in vivo evaluation of
✍ Gopal Pathuri; Hrushikesh B. Agashe; Vibhudutta Awasthi; Hariprasad Gali 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 174 KB

## Abstract Formation of islet amyloid deposits contributes to the progressive loss of beta‐cells in Type 2 diabetes. Islet amyloid is composed of islet amyloid polypeptide (IAPP). [(N‐Me)G^24^, (N‐Me)I^26^]hIAPP(22–27) peptide was found to bind human IAPP with high‐affinity and inhibit fibrillogen

Synthesis and in vivo evaluation of a ne
✍ Futoshi Takao; Shigeki Sasaki; Minoru Maeda; Toshimitsu Fukumura; Takashi Tahara 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 314 KB

## Abstract __N__‐[(1‐Ethyl‐2‐pyrrolidinyl)methyl]‐5‐(2‐[^18^F]fluoroethyl)‐2,3‐dihydroben‐zofuran‐7‐carboxamide ([^18^F]5) was synthesized __via__ nucleophilic substitution with K^18^F/Kryptofix222 complex in 5.4∼6.8% radiochemical yields with a specific activity of larger than 5.6 TBq/mmol (150 C