Labelled compounds of interest as antitumour agents - V. Syntheses of [18O]-5-methylisoquinolinone and 1-(furan-2-yl-[18O]-methoxy)-5-methylisoquinoline: Correction (J. Labelled Cpd Radiopharm.38: 935)

Labelled compounds of interest as antitu

Labelled compounds of interest as antitumour agents-v1. Syntheses of [18O]-5-methylisoquinolinone and 1-(furan-2-yl-[18O]-methoxy)-5-methylisoquinoline

✍ Jane M. Berry; Michael D. Threadgill 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 314 KB 👁 1 views

Treatment of 2-methylcinnamic acid with HzL80 at 1 OOOC under acidic conditions leads to high incorporation of I80 by exchange. Methods have been developed for chemically and isotopically efficient conversion to the corresponding [~arbonyl-'~O] methyl ester, to ['80]-5-methylisoquinolinone (an inhib