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Labeling of monoclonal antibodies with 153Sm for potential use in radioimmunotherapy

โœ Scribed by M Fani; S Vranjes; S.C Archimandritis; S Potamianos; S Xanthopoulos; P Bouziotis; A.D Varvarigou


Book ID
108482253
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
161 KB
Volume
57
Category
Article
ISSN
0969-8043

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Endoglin (CD105), which is a component of the TGF-โค receptor complex, is highly expressed at the surface of proliferating human endothelial cells such as those of tumor vessels. In the present study, we tested the antitumor efficacy of 125 I-labeled anti-endoglin monoclonal antibodies (MAbs), SN6f a