Label-Free Detection of Few Copies of DNA with Carbon Nanotube Impedance Biosensors
β Scribed by Tetiana Kurkina; Dr. Alexis Vlandas; Dr. Ashraf Ahmad; Prof. Klaus Kern; Dr. Kannan Balasubramanian
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 765 KB
- Volume
- 123
- Category
- Article
- ISSN
- 0044-8249
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The fabrication of biosensors via self-assembly of single-walled carbon nanotubes (SWNTs) and DNA on a platinum electrode was presented in this paper. The carboxylic SWNTs were assembled on an aminemodified platinum electrode surface and followed by the assembly of NH 2 -DNA with the carboxyl-amine
## Abstract Actinomycin D or proflavine which are known to intercalate within the helix of doubleβstranded DNA (dsDNA) are used as labelβfree control to unequivocally prove complementary DNA hybridization by means of electrochemical impedance spectroscopy (EIS). Based on a carefully designed interf