DNA biosensor by self-assembly of carbon nanotubes and DNA to detect riboflavin

✍ Scribed by Jing Li; Yunhuai Zhang; Tongyi Yang; Huai Zhang; Yixuan Yang; Peng Xiao

• Publisher: Elsevier Science
• Year: 2009
• Tongue: English
• Weight: 749 KB
• Volume: 29
• Category: Article
• ISSN: 0928-4931
• DOI: 10.1016/j.msec.2009.06.006

✦ Synopsis

The fabrication of biosensors via self-assembly of single-walled carbon nanotubes (SWNTs) and DNA on a platinum electrode was presented in this paper. The carboxylic SWNTs were assembled on an aminemodified platinum electrode surface and followed by the assembly of NH 2 -DNA with the carboxyl-amine coupling. The decorated surface was characterized by Field Emission Electron Microscopy (FEG-SEM) and electrochemical experiments, which showed that the reaction of DNA-SWNTs biosensor was quasireversible. The mechanism of DNA and riboflavin (VB 2 ) was studied by cyclic voltammetry and UV-Vis spectroscopy. The fabricated SWNTs-reinforced biosensor exhibits high sensitivity and low detection limit for the tested VB 2 compared to the reported methods.