✦ LIBER ✦

Label-free biochemical characterization of stem cells using vibrational spectroscopy

✍ Scribed by James W. Chan; Deborah K. Lieu

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 685 KB
Volume: 2
Category: Article
ISSN: 1864-063X
DOI: 10.1002/jbio.200910041

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✦ Synopsis

Abstract

Raman and infrared (IR) spectroscopy are two complementary vibrational spectroscopic techniques that have experienced a tremendous growth in their use in biological and biomedical research. This is, in large part, due to their unique capability of providing label‐free intrinsic chemical information of living biological samples at tissue, cellular, or sub‐cellular resolutions. This article reviews recent developments in applying these techniques for the characterization of stem cells. A discussion of the potential for these methods to address some of the major challenges in stem cell research is presented, as well as the technological and scientific advancements that are needed to progress the knowledge in the field. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

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