Label-free and homogeneous DNA hybridization detection using gold nanoparticles-based chemiluiminescence system
โ Scribed by Yingying Qi; Baoxin Li; Zhujun Zhang
- Book ID
- 108072104
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 605 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0956-5663
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract We report a highly sensitive method for detecting DNA hybridization by anodicโstripping voltammetry, using assemblies of AuNPs as electrochemical labels. The assemblies are made by layerโbyโlayer modification of subโmicrometer latex spheres, followed by the uptake of the negatively char
## Abstract Actinomycin D or proflavine which are known to intercalate within the helix of doubleโstranded DNA (dsDNA) are used as labelโfree control to unequivocally prove complementary DNA hybridization by means of electrochemical impedance spectroscopy (EIS). Based on a carefully designed interf
We report a label-free, aptamer-based chemiluminescent biosensor. The biosensor relies upon the catalytic activity of unmodified gold nanoparticles (AuNPs) on the luminol-H 2 O 2 chemiluminescence (CL) reaction, and the interaction of unmodified AuNPs with the aptamer. The unmodified AuNPs can effec