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Chemiluminescent detection of DNA hybridization using gold nanoparticles as labels

✍ Scribed by Zheng-Ping Li; Cheng-Hui Liu; Yong-Shan Fan; Xin-Rui Duan

Publisher: Springer
Year: 2006
Tongue: English
Weight: 206 KB
Volume: 387
Category: Article
ISSN: 1618-2650
DOI: 10.1007/s00216-006-0914-3

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## Abstract We report a highly sensitive method for detecting DNA hybridization by anodic‐stripping voltammetry, using assemblies of AuNPs as electrochemical labels. The assemblies are made by layer‐by‐layer modification of sub‐micrometer latex spheres, followed by the uptake of the negatively char