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L8027 and 1-nonyl-imidazole as non-selective inhibitors of thromboxane synthesis

โœ Scribed by Arthur V. Prancan; Jean Lefort; Michel Chignard; Kyriaki Gerozissis; Fernand Dray; Bernardo B. Vargaftig


Book ID
115875605
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
870 KB
Volume
60
Category
Article
ISSN
0014-2999

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## Abstract ฮฑโ€Aminoketone hydrochlorides **2aโ€”d** were synthesized by Dakinโ€West reaction from __L__โ€phenylalanine and __L__โ€cyclohexylalanine followed by hydrolysis in acidic medium. Treatment of **2aโ€”d** with aqueous potassium thiocyanate afforded 1, 3โ€imidazoleโ€2โ€thiones **3aโ€”d** which were alky