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l -tetrahydropalamatine: a potential new medication for the treatment of cocaine addiction

โœ Scribed by Wang, Jia Bei; Mantsch, John R


Book ID
120028205
Publisher
Future Science
Year
2012
Tongue
English
Weight
865 KB
Volume
4
Category
Article
ISSN
1756-8919

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Cocaine's addictive liability has been linked to its pharmacologic actions on mesotelencephalic dopamine (DA) reinforcement/reward pathways in the central nervous system (CNS). Dopaminergic transmission within these pathways is modulated by gamma-aminobutyric acid (GABA). With this knowledge, we exa