Properties of ฮฑ-l-iduronidase in culture
Properties of ฮฑ-l-iduronidase in cultured skin fibroblasts from ฮฑ-l-iduronidase-deficient patients
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S. Fujibayashi; R. Minami; Y. Ishikawa; K. Wagatsuma; T. Nakao; S. Tsugawa
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Article
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1984
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Springer
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English
โ 324 KB
On DEAE cellulose column chromatography, alpha-L-iduronidase in cultured skin fibroblasts was resolved into two distinct components, forms A and B. They had similar Km values for 4-methylumbelliferyl-alpha-L-iduronide, but differed in pH optima and thermal stability. Form B was more heat-stable than