L-asparaginase as a marker of chemotherapy dose modification in children with acute lymphoblastic leukemia
β Scribed by Jacques Baillargeon; Anne-Marie Langevin; Margaret Lewis; Paul J. Thomas; Judith Mullins; John Dugan; Brad H. Pollock
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 85 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND Thrombotic events (TEs) are serious secondary complications in children with acute lymphoblastic leukemia (ALL) who receive Lβasparaginase (ASP) therapy; however, the prevalence of TEs has not been established. The primary objective of the Prophylactic Antithrombin Replac
Methotrexate (MTX) infusions of 500-1,000 mg/m2 over 24 hours may improve survival and prevent relapse in children with acute lymphoblastic leukemia (ALL). Childrens Cancer Group (CCG) Study 139 compared weekly oral methotrexate 20 mg/m2/ week (oral MTX) to MTX 500 mg/m2 infused over 24 hours (IV MT