Second remission induction rates for vincristine and prednisone alone (VP) and vincristine, L-asparaginase, and prednisone (VLP) are compared for children with acute lymphocytic leukemia. No evidence of a significant difference between the second induction complete remission rate for VP (78.6%) and
Vincristine, prednisone and L-asparaginase in the induction of remission in children with acute lymphoblastic leukemia following relapse
β Scribed by F. H. Kung; W. L. Nyhan; J. Cuttner; G. Falkson; P. Lanzkowsky; V. Del Duca; I. U. Nawabi; K. Koch; H. Pluess; A. Freeman; E. O. Burgert; L. A. Leone; F. Ruymann; R. B. Patterson; T. Degnan; N. Hakami; T. F. Pajak; James Holland
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 548 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Background: The authors report the occurrence of fatal or near-fatal sepsis in 16 of 38 children with newly diagnosed acute lymphoblastic leukemia (all) treated with a new induction regimen that differed from its predecessor by the substitution of dexamethasone for prednisone. ## Methods: The
Therapy for acute lymphocytic leukemia (ALL) has been less successful in adults than in children. Many centers treat all adult leukemia with the same regimen. We have used vincristine and prednisone for initial therapy in 14 adults with ALL since 1971 and have followed a treatment regimen developed
A remission-induction regimen for childhood leukemia using cyclophosphamide, asparaginase, vincristine, and prednisone (CAVP) was compared to standard vincristine-prednisone (VP) induction. The more intensive regimen was associated with a lower complete remission rate (81% vs 93%) and a higher early
## Abstract ## BACKGROUND. The authors evaluated the response rate, toxicity, and pharmacokinetics of topotecan given before standard induction therapy for childhood acute lymphoblastic leukemia (ALL) in first relapse. ## METHODS. Patients received topotecan (2.4 mg/m^2^ daily as a 30βminute inf