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Koilocytosis: A Cooperative Interaction between the Human Papillomavirus E5 and E6 Oncoproteins

✍ Scribed by Ewa Krawczyk; Frank A. Suprynowicz; Xuefeng Liu; Yuhai Dai; Dan P. Hartmann; John Hanover; Richard Schlegel

Book ID
117970810
Publisher
American Society for Investigative Pathology
Year
2008
Tongue
English
Weight
437 KB
Volume
173
Category
Article
ISSN
0002-9440

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## Abstract The E2 protein of the papillomavirus plays an essential role in the viral life cycle. Through a yeast two‐hybrid screening, human polo‐like kinase 1 was found to interact with human papillomavirus type 5 E2. Further characterization identified that the domains responsible for the intera