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Kinetic Analysis of the Interactions of Human Papillomavirus E6 Oncoproteins with the Ubiquitin Ligase E6AP Using Surface Plasmon Resonance

✍ Scribed by Katia Zanier; Sebastian Charbonnier; Mireille Baltzinger; Yves Nominé; Danièle Altschuh; Gilles Travé

Book ID
116662114
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
485 KB
Volume
349
Category
Article
ISSN
0022-2836

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Human scribble (hScrib), which was identified as substrate of human papillomavirus (HPV) E6 for ubiquitin-mediated degradation dependent on ubiquitin-protein ligase E6AP, is a human homolog of Drosophila neoplastic tumor suppressor scribble, in which mutation causes loss of polarity and overgrowth o