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Knock-down of methyl CpG-binding protein 2 (MeCP2) causes alterations in cell proliferation and nuclear lamins expression in mammalian cells

โœ Scribed by Babbio, Federica; Castiglioni, Ilaria; Cassina, Chiara; Gariboldi, Marzia; Pistore, Christian; Magnani, Elena; Badaracco, Gianfranco; Monti, Elena; Bonapace, Ian


Book ID
119894383
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
773 KB
Volume
13
Category
Article
ISSN
1471-2121

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## Abstract Mutations in the MeCP2 gene cause Rett syndrome, a neurologic condition affecting primarily young girls. To gain insight into the normal function of MeCP2, we examined its temporal and spatial expression patterns, and immunoreactive prevalence, during late embryonic and perinatal brain