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HCV NS2 protein inhibits cell proliferation and induces cell cycle arrest in the S-phase in mammalian cells through down-regulation of cyclin A expression

✍ Scribed by Xiao-Jun Yang; Jing Liu; Li Ye; Qing-Jiao Liao; Jian-Guo Wu; Jin-Rong Gao; Ying-Long She; Zheng-Hui Wu; Lin-Bai Ye

Book ID: 116967746
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 589 KB
Volume: 121
Category: Article
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2006.02.004

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## Abstract Adult neurons are generally accepted to be in a quiescent, nonproliferative state. However, it is becoming increasingly apparent that, in Alzheimer's disease (AD), alterations in cell cycle machinery, suggesting an attempt to reenter cell cycle, relate temporally and topographically to