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Klotho is a substrate for α-, β- and γ-secretase

✍ Scribed by Laura Bloch; Olga Sineshchekova; Daniela Reichenbach; Karina Reiss; Paul Saftig; Makoto Kuro-o; Christoph Kaether


Book ID
113621561
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
407 KB
Volume
583
Category
Article
ISSN
0014-5793

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MUC1 is a substrate for γ-secretase
✍ JoAnne Julian; Neeraja Dharmaraj; Daniel D. Carson 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB

## Abstract Understanding the underlying mechanisms by which a normal cell avoids the oncogenic potential of MUC1 signaling requires further definition of the pathways by which the MUC1 cytoplasmic tail is processed in both normal and tumor‐derived cells. In the present study we describe the proces