Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors
β Scribed by J.F. Morrison
- Book ID
- 115732131
- Publisher
- Elsevier Science
- Year
- 1969
- Weight
- 1015 KB
- Volume
- 185
- Category
- Article
- ISSN
- 0005-2744
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π SIMILAR VOLUMES
## Determination of tight-binding inhibition constants by nonlinear least-squares regression requires sufficiently good initial estimates of the best-fit values. Normally an initial estimate of the inhibition constant must be provided by the investigator. This paper describes an automatic procedur
Active site titration by a reversible tight-binding inhibitor normally depends on prior knowledge of the inhibition constant. Conversely, the determination of tight-binding inhibition constants normally requires prior knowledge of the active enzyme concentration. Often, neither of these quantities i