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Kinetics of N-Formylation of Piperidine and Related Compounds

✍ Scribed by L. Maat; M. Peereboom


Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
146 KB
Volume
92
Category
Article
ISSN
0037-9646

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✦ Synopsis


The kinetics of the N-formylation of piperidine and 3-methylpiperidine with chloral hydrate and 1,2,3,4-tetrahydroisoquinoline with chloral in toluene, have been investigated. The reactions are first order in both reactants. The formylation of piperidine is faster than that of I ,2,3,4-tetrahydroisoquinoline and somewhat slower than that of 3-methylpiperidine.


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