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Kinetics of Drug Action in Disease States. XXII. Effects of Contraceptive Steroids on the Pharmacodynamics of Ethanol in Rats

โœ Scribed by Sompon Wanwimolruk; Gerhard Levy


Book ID
119651317
Publisher
Springer US
Year
1987
Tongue
English
Weight
655 KB
Volume
04
Category
Article
ISSN
0724-8741

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Kinetics of drug action in disease state
โœ Masafumi Hisaoka; Gerhard Levy ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 486 KB ๐Ÿ‘ 1 views

The purpose of this investigation was to determine if the reported prolongation of barbiturate-and ethanol-induced sleeping times by nicotine in rodents are pharmacodynamic or pharmacokinetic interactions. Adult female rats were pretreated with nicotine, either 0.5 or 1.5 mg/kg ip acutely or 0.5 mg/